Microneedle patch delivery to the skin of virus-like particles containing heterologous M2e extracellular domains of influenza virus induces broad heterosubtypic cross-protection
نویسندگان
چکیده
منابع مشابه
Long-Lasting B- and T-Cell Responses in Virus-Like Particles to the Skin Induces Microneedle Delivery of H5N1 Influenza
Published Ahead of Print 14 July 2010. 10.1128/CVI.00100-10. 2010, 17(9):1381. DOI: Clin. Vaccine Immunol. Sang-Moo Kang Donis, Mark R. Prausnitz, Richard W. Compans and Li-Mei Chen, Fu-Shi Quan, James C. Birchall, Ruben O. Pearton, C. Todd Davis, Dae-Goon Yoo, Kyoung-Mi Park, Jae-Min Song, Yeu-Chun Kim, Aleksandr S. Lipatov, Marc Mice Long-Lasting Band T-Cell Responses in Virus-Like Particles ...
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Influenza virus M2 extracellular domain (M2e) has been a target for developing cross-protective vaccines. However, the efficacy and immune correlates of M2e vaccination are poorly understood in the different host genetic backgrounds in comparison with influenza vaccines. We previously reported the cross-protective efficacy of virus-like particle (M2e5x VLP) vaccines containing heterologous tand...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2015
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2015.05.278